Genetic factors
Hereditary deafness is an inherited condition that is either present at birth or develops throughout a person’s life. It’s caused by gene mutations that can result in hearing loss, meaning individuals are predisposed to the condition. Examples include Pendred syndrome and otosclerosis.
Certain medications
Ototoxic drugs, such as certain NSAIDs and cancer medications, water pills and diuretics, and some antibiotics such as aminoglycosides, can cause hearing loss or deafness.
Trauma
Injuries caused by trauma such as changes in air pressure, a hole in or perforation of the eardrum, or head injuries like skull fractures or a traumatic brain injury can also cause hearing loss.
Certain diseases
There are a variety of diseases that can cause hearing loss, including bacterial meningitis, mumps, herpes, Lyme disease and Meniere’s disease.
Other causes
There are a variety of other causes of deafness, including:
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viral infections and other ear conditions, such as impacted earwax
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abnormal bone growths or tumours, such as an acoustic neuroma
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exposure to certain toxic chemicals
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smoking
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nutritional deficiencies
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obesity